Seizures and PDD – the What, How and Why?

Neurons Firing During Seizure

Neurons Firing During Seizure

Seizures are something we associate with Epilepsy. — a brian disorder in which multiple, unexpected seizures are triggered. Seizures are also a very common symptom of Pervasive Development Disorders (PDD) including Autism.

The Basics – What Is a Seizure?

Seizures themselves are highly studied. Seizures occur when there is abnormal electrical activity in the brain. There are times in which the brain’s neurons all fire simultaneously, and this is what causes a seizure to occur. The majority of people think of a seizure as the violent convulsing,  unconscious episode that people have. This is true – some seizures, known as tonic clonic seizures are characterized by uncontrollable and violent shaking. This is because both sides of the brain are affected. However, a partial seizure – only affecting part of the brain – can be as mild as losing awareness for a brief amount of time. The recurrence of seizures is known as Epilepsy, however, seizures can occur in people who do not have epilepsy as well.

Because seizures have so many symptoms, and can sometimes affect different parts of the body, they are classified into motor, sensory, autonomic, emotional, or cognitive.

Why Seizures Occur in PDD and Autism Cases

It has been found that one in four children with a PDD will develop seizures. Most recent studies conclude that 1/3 of Autistic children will also develop epilepsy. Though it was heavily documented in the 1960′s when the connection between Autism and Seizures was studied, researches even today are working hard to establish links between seizures and Autism.

Another interesting study is that the chances of developing seizures range based upon which subcategory of PDD that the person has. The present studies suggest that people with classical Autism have a 30% risk of having seizures, while those with Asperger Syndrome have less than a 10% risk. Those with Disintegrative Disorder or Rett Syndrome have over 75% chance of developing seizures. What this shows us is that there are risk factors – specifically in Autism – that determine the risk of a person who has PDD developing seizures.

The major risk factors for a child with Autism developing seizures is the level of cognitive impairment and motor deficits. The more common symptoms of Autism – clumsiness, fine motor coordination, aren’t as severe as paralysis on one side or forms of cerebral palsy. The more severe the cognitive impairment, in some cases, the greater the risk for developing seizures. In a child with Autism, who has normal intelligence and no other apparent mental condition or family history of seizures, the chance of them developing seizures is less than 10%. However, if the Autistic child has mental retardation or severe motor deficit, the risk rises to 50%

Treating Seizures

Sometimes, seizures give a signal of their onset. Some sufferers report a strange taste in their mouths, sudden body temperature change, etc. Sometimes, they are unexpected. Typically, seizures can be controlled with medication. It’s very important that the type of seizure, whether or not its epilepsy, and the underlying cause of the seizures is studied as to provide the appropriate medication.

Comments

  1. elizabeth says

    Hi,

    Just a note on seizures related to autism and other disorders. My son is aphasiac and while not diagnosed with autism (rather hypoxia from a knotted cord at birth) he is very similar to an autistic child (and down’s syndrome as well). It is my belief that autism is brain injury, which is the same belief espoused by the Institutes for the Achievement of Human Potential in Philadelphia, which has been working with brain injured children for 60 years. The Discovery Magazine had an amazing article, which has all been quashed which had significant findings for the cause of autism. Their findings had to do with environmental toxins while in utero to be a direct causal factor. It would be important if this was brought out into the open. Furthermore, regarding seizures, I think parents are looking for natural solutions to their children’s seizures. Our son has psychomotor seizures, which is more found in the autistic population. In desperation, we tried GABA, which gave us literally amazing results, as it NORMALIZES neurotransmitter levels. (His dopamine levels are always too high) AND it has been shown through medical research to mitigate or nullify seizures. We have been seizure free for 4 years and we feel lucky, especially as he is now a six foot 200 pound 17 years old!!! AMA seizure meds are known to be toxic. Let’s all try to get away from the toxicity!!!!!!!!!!!!!!

    Just some thoughts!

    Elizabeth

  2. priya says

    hi,
    we are in the same position too. will help if u let usknow which doc u went to for the seizures. my daughter is on antiepileptics for the past 11 years nad still not out of the problem though temporarily everything seems to be under ocntrol. if u can share inofrmation i will be grateful.

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